Sulfobutyl Ether Beta-Cyclodextrin Sodium Salt Other cyclodextrins can not be replaced

Cyclodextrin and its derivatives can be used for the inclusion of drugs mainly peptides, protein hormones, such as glucagon, salmon calcitonin, adrenocorticotropic hormone analogues, insulin, peptide Rui Lin, luteinizing hormone releasing hormone.

Sulfobutyl ether betacyclodextrin sodium salt as a new type of pharmaceutical excipients, negatively charged SBE-β-CD with other derivatives unparalleled advantages. It can be seen from the recent research that SBE-β-CD has a special charge and affinity to the nitrogen-containing drugs which can form a positive charge, which can increase the solubility and stability of the drug better , To improve the bioavailability of drugs to improve drug release rate and reduce the local irritation of drugs to reduce the volatility of drugs to reduce side effects, cover up the bad smell of small renal toxicity. At present, SBE-β-CD in injection, oral medication, nasal drug, eye medication has been a better application.

Shandong Binzhou Zhi Yuan Biotechnology Co., Ltd. specializes in the production of sodium butyl ether butyl cyclodextrin sodium. The product has been approved by the State Food and Drug Administration: drug registration acceptance notice, admissibility number: CXFS1500004 Lu, and access to clinical approval; also adopted by the US Food and Drug Administration DMF record, the record number: 030167.

Product name : Piroxicam Beta Cyclodextrin
Product No. : P-β-CD
CAS No. : 96684-39-8

Appearance : Light yellow powder

Piroxicam beta Cyclodextrin

 














Details:

Piroxicam belongs to one kind of non-steroidal anti-inflammatory drug, with strong anti-inflammatory effect, difficult to dissolve in water and absorb slowly, easy to cause gastrointestinal bleeding and gastric ulcer after oral administration. Intramuscular injection may cause pain at the injection site and mild tissue necrosis. Piroxican is made into Piroxicam-Beta-Cyclodextrin inclusion complex, can accelerate the dissolution rate of drugs, reduce the irritation for gastrointestinal tract. The oral analgesics Cycladol is a successful application of piroxicam-β-cyclodextrin inclusion complex.

Piroxicam-Beta-Cyclodextrin is refined and made by pharmaceutical grade Piroxicam and pharmaceutical grade β-cyclodextrin inclusion, according to certain proportion with unique new technology. The inclusion compound owns lower odor, stronger stability and more stable drug release rate, comparing with Piroxicam monomer, mainly applied in Anti-inflammatory analgesic drugs ointment.    


Cyclodextrin Inclusion Compound

Cyclodextrin Inclusion Compound,Beta Cyclodextrin Compound,Carbohydrate Compound 7585-39-9,White Cyclodextrin Inclusion Compound

Zhiyuan Biotchnology , http://www.zycydextrin.com