The botulinum toxin type A toxin is extremely toxic and it destroys a protein called SNAP-25, which cuts off communication between nerve cells and paralyzes muscles.
Italian researchers found through animal experiments that the type A toxin secreted by Botox, which is the main ingredient of Botox, is injected into the skin and may enter the central nervous system and even reach the brain stem. This finding once again raised concerns about the safety of botulinum toxin wrinkle removal.
The botulinum toxin type A toxin is extremely toxic and it destroys a protein called SNAP-25, which cuts off communication between nerve cells and paralyzes muscles. This function of the botulinum toxin type A toxin has been used to treat strabismus and muscle spasms, etc. Later, the cosmetic surgeon began to paralyze the facial muscles with the toxin to achieve the effect of removing wrinkles.
The United States "Science" magazine website reported a few days ago, an Italian research group conducted experiments using botulinum type A toxins for the treatment of epilepsy. They injected toxins on the brain's side of rats with epilepsy, but they found the toxin on the other side of the brain. The researchers then inject toxins into the eyes, toes and brain of normal mice and rats. The results of the SNAP-25 protein chase study showed that the botulinum toxin type A toxin can move from the injection site to the peripheral nervous system and sometimes reach the brain stem.
The U.S. Food and Drug Administration has already begun investigations on the deaths of botulinum toxins that had previously been reported by the U.S. media. Although the results of the new study once again cast doubt on the safety of botulinum toxin detoxification, some scientists believe that there is no need to worry too much. Neuroscientist Christopher Van Baseld of the University of Nevada in the United States said that botulinum toxin can be used safely as long as the injection is not excessive.