Antibiotics have been used as feed promoters for more than 60 years (Moore, 1946; Jukes, 1950). The long-term use of antibiotic-containing feed for livestock and poultry has led to an increase in microbial resistance in the body, and the animal's resistance to disease is getting worse and worse, and the dose of antibiotics for treating diseases is increasing. Increase the resistance of microorganisms in the human body.
According to statistics from the Chinese Academy of Sciences, China uses about 162,000 tons of antibiotics a year, 52% of which are veterinary, and more than 50,000 tons of antibiotics are discharged into the water and soil environment, causing environmental pollution. On March 14, 2019, the Ministry of Agriculture and Rural Affairs issued a request for the “Drug Feed Additives Exit Plan (Draft for Comment)â€, and feed-promoting antibiotics will be completely banned from July 1, 2020.
How to choose the appropriate substitute is imminent, the ideal growth-promoting antibiotic should have the following twelve typical characteristics:
1, no toxic side effects;
2, easy to be removed by the body;
3, the environment has no residue;
4, no bacterial resistance;
5, stable in the feed;
6, stable in the digestive tract
7, no adverse effects on animal palatability;
8, does not destroy the normal intestinal flora;
9, can kill pathogenic bacteria;
10, can improve animal disease resistance;
11, can improve feed conversion efficiency;
12. It has a growth promoting function.
At present, it has not been found that a single substitute product can meet the above requirements at the same time. Therefore, it is the most feasible solution to replace the growth-promoting antibiotics by effectively combining the multiple types of products to meet the above requirements.
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